Rheinhessen (in English often Rhine-Hesse or Rhenish Hesse) is the largest of 13 German wine regions for quality wines (QbA and Prädikatswein) Named for the traditional region of Rhenish Hesse, it lies on the left bank of the River Rhine between Worms and Bingen in the federal state of Rhineland-Palatinate. Riesling is the most planted variety here and it's the source of the infamous Liebfraumilch.